Medicine Chemistry MCQ's

 

1. Aspirin is introduced by_________in 1889

A. Dreser's

B. Emil Fischer and Mering

C. Barger and Dale

D. None of above

2. Name of this aromatic ring is

A. Azopane

B. Azepine

C. Azepane

D. None of above

3. Name of this aromatic ring is

A. Diphenylmethyl ethane

B. 2-ethyl-1-methyl naphthalene

C. 1-ethyl-2-methyl naphthalene

D. 1-ethyl-1-methyl naphthalene

4. The hetroaromatic redical is called

A. Anthryl

B. Naphthyl

C. Phenanthryl

D. Dibenzyl

5. Oxadiazole ring contains

A. 1 Nitrogen /Oxygen

B. 2 Oxygen/ Nitrogen

C. 2 Nitrogen/Sulphur

D. 2 Nitrogen/Oxygen

6. Which of the following reactions is catalyzed by the enzyme adenylate cyclase?

A. Conversion of ATP to cyclic AMP

B. Conversion of cyclic AMP to AMP

C. Conversion of cyclic AMP to ATP

D. Conversion of AMP to cyclic AMP

7. How many main families of GPCRs are there?

A. 5

B. 6

C. 7

D. 4

8. The main goals of pre-clinical studies

A. To determine the safe dose for first-in-man study

B. To assess a product's safety profile

C. A and B both

D. None

9. IND stands for

A. Improved new drug

B. Investigational new drug

C. International new drug

D. International novel drug

10. Human micro dosing studies conducted in which clinical phase ?

A. Phase 0

B. Phase I

C. Phase II

D. Phase III

11. MTD is

A. Maximum targeted dose

B. Minimum tolerated dose

C. Minimum targeted dose

D. Maximum tolerated dose

12. Single ascending dose studies are done in_____

A. Phase lb

B. Phase Ia

C. Phase II

D. Phase Ila

13. NDA is

A. New Drug Application

B. New Drug approval

C. Noval Drug Admistration

D. New Drug agenda

14. Phase IV trial is also known

A. Base of clinical trial

B. Multiple ascending dose era

C. Post marketing Surveillance

D. Pre-clinical trial

15. How many people will be selected for phase I trial?

A. The whole market will be under surveillance

B. 300-3000 people

C. 20-300 people

D. 20-50 people

16. How many people will be selected for phase II trial?

A. The whole market will be under surveillance

B. 300-3000 people

C. 20-300 people

D. 20-50 people

17. How many people will be selected for phase III trial?

A. The whole market will be under surveillance

B. 300-3000 people

C. 20-300 people

D. 20-50 people

18. Which one of the following will be checked under phase IV surveillance?

A. The whole market will be under surveillance

B. 300-3000 people

C. 20-300 people

D. 20-50 people

19. Precision Medicine is an emerging approach depending on

A. Genomic study of individual

B. Diagnostic process of individual

C. Diseases conditions

D. None of above

20. Compound with good activity and selectivity in screening during drug discovery isknown as

A. Hit

B. Lead

C. NDA

D. IND

21. Natural products or derivatives or synthetic substances with good binding ability in Drug discovery is known as

A. Hit

B. Lead

C. NDA

D. IND

22. The process of bringing a new pharmaceutical drug to the market once the lead compound has been identified through the process of drug discovery. (From Lead to NDA) is known as

A. Drug discovery

B. Drug development

C. Both of above

D. None of above

23. Identification of a new chemical entity as a potential therapeutic agent (From Hit to Lead)is known as

A. Drug discovery

B. Drug development

C. Both of above

D. None of above

24.  Who is founder of modem medicine?

A. Hippocartes

B. Clark

C. Charak

D. Henry's

25. First hormone epinephrine was synthesized in Year

A. 1903

B. 1904

C. 1909

D. 1889