Medicines

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Below are listed some of the common drugs used in feline medicine. See the FDA Green book for a comprehensive list of approved veterinary medicines. See also compounding pharmacies

Drug (cats)	Indications	Dose	Route	Frequency
Acarbose	Diabetes mellitus	12.5 - 20 mg	Oral	with each meal
Acemannan (Aloe vera derivative)	Immunomodulation	1-2 mg/kg	Intralesional, IP or SQ	weekly
Acepromazine (ACP)	Sedation, restraint	0.05-2.25 mg/kg	SQ, IM, PO	q 8-12hrs
	Aortic thromboembolism	0.15-0.3 mg/kg	SQ	q 8-12hrs
	Amphetamine toxicosis	0.05 -1.0 mg/kg	IV, IM, SQ	q 8-12hrs
Acetazolamide	Glaucoma	5-10 mg/kg	PO	q 8-12hrs
Acetylcysteine	Mucolytic (Asthma), Acetaminophen toxicity	140 mg/kg	IV	loading dose
		5-10 mg/kg	PO	every 12 hours
Acetylsalicylic acid	Antipyretic	6-10 mg/kg	PO	q 48 - 72hrs
	Antithrombotic	80 mg/cat or 25 mg/kg	PO	2 times/wk
	Anti-inflammatory	10-20 mg/kg	PO	q 48 hrs
	Analgesia	10 mg/kg	PO	q 48hrs
Actinomycin D	Chemotherapy / antimicrobial	0.5-0.9 mg/m²	IV	once every 3 weeks
Acyclovir	Anti-herpes viral	200 mg	PO	q 6hrs
S-Adenosylmethionine	Glutathione replenisher - feline inflammatory liver disease	20-30 mg/kg	PO	q 24hrs
Aglepristone	Mammary hyperplasia, Induces abortion	10mg/kg	SQ	Days 1, 2, 7 & 14
	Mesalliance	10mg/kg	SQ	stat
Albendazole	Lungworm	50 mg/kg	PO	daily for 21 days
Albuterol sulphate (Salbutamol)	Bronchodilation	90 µg metered dose	inhaler	q 6 - 8hrs
Alfaxan (Alfaxalone/alfadalone)	Intravenous anesthetic	1 - 2 mL per 5 kg bodyweight	IV	bolus or slowly IV
Allopurinol	Urate uroliths	10 mg/kg	PO	q 8 - 12hrs for 30 days
Alprazolam (Benzodiazepine)	Elimination behavioural problems	0.125-0.25 mg/cat	PO	q 12hrs
Aluminium carbonate gel	Phosphate binder	10-30 mg/kg	PO with meals	q 8hrs
Aluminium hydroxide	Antacid	20-30 ml	PO	q 2 - 4hrs
	Phosphate binder	30-90 mg/kg	PO with meals	q 8 - 24hrs
Amantadine	Analgesia for chronic pain	3-5 mg/kg	PO	daily for 7-14 days
Ambex	Broad-spectrum anthelmintic	1 tablet per 5 kg	PO	every 3 months
Amikacin	Susceptible infections	15-22 mg/kg	IM, IV, SQ	q 24hrs
Aminopentamide (Centrine)	Diarrhoea	0.1 mg/cat	SC, IM, PO	q 8 - 12hrs
Aminophylline	Asthma	4-6.6 mg/kg	PO	q 8 - 12hrs; use with caution in cats
		2-5 mg/kg	IV infusion	q 12hrs
Aminopromazine	Smooth muscle relaxant	2.0-4.5 mg/kg	PO	q 12hrs
5-aminosalicylic acid	Irritable bowel disease	20 mg/kg	PO	q 24hrs
Amitriptyline (Endep-10)	Behaviour, urine spraying	2 mg/kg or 5-10 mg/cat	PO	q 24hrs
Amlodipine besylate (Norvasc)	Systemic hypertension	0.625 mg/cat	PO	q 24hrs
Ammonium chloride	Struvite dissolution	800 mg/cat	PO	q 24hrs
Amoxicillin/clavulanate	Susceptible infections	10-20 mg/kg	PO	q 12hrs
Amoxil (Amoxicillin)	Susceptible infections	4-11 mg/kg	PO	q 12hrs
Amphetamine	CNS stimulation during certain toxicoses	5 mg/cat	PO	q 12hrs
Amphotericin B	Systemic mycoses	0.15-1 mg/kg in 5% dextrose	IV	q 48hrs to a total cumulative dose of 10mg/kg
			SQ	diluted 1:10 in saline
Ampicillin	Susceptible infections	20-60 mg/kg	PO	q 8 - 12hrs
Amprolium	Coccidiosis	60-100 mg/kg	PO	q 24hrs x 5 d
	With sulfadimethoxine	150 mg/kg	PO	q 24hrs x 5d
Aprotinin	Protease inhibitor (Pancreatitis), fibrinolytic agent	5000 KUI (kallikrein inhibitor units)/kg	IP	q 6 - 8hrs
Ascorbic acid (Vitamin C)	Feline infectious peritonitis	25-125 mg/kg/day	PO	q 24hrs
	Acetaminophen toxicosis	30 mg/kg	PO, SQ	6x7 treatments
Asparaginase	Lymphosarcoma	10,000 U/m²	IV	weekly as part of a protocol
Aspirin	Antipyretic	6-10 mg/kg	PO	q 48 - 72hrs
Atenolol (Tenormin)	ß₁-blocker for Hypertrophic cardiomyopathy + Hypertension	6.25 mg/cat	PO	q 24hrs
Atipamezole (Antisedan)	Medetomidine reversal	equivolume	IM	as needed
Atovaquone	Toxoplasma, Pneumocystis spp	13.3 mg/kg with fatty meal	PO	q 8hrs x 21 days
Atracurium	Paralytic anaesthetic agent	0.1-0.25 mg/kg	IV	repeated q 30mins
Atropine	Pre-anaesthetic medicant, Sinus bradycardia	0.02-0.04 mg/kg	IM, IV, SQ	as required
	Organophosphate toxicity	0.2-2.0 mg/kg	IM, SQ	q 2hrs
Aurothioglucose	Pemphigus, Gingivitis and podomatitis	2 mg	IM	stat, then 1 mg/kg weekly
Azathioprine	Enteritis	0.2-0.3 mg/kg	PO	q 24-48hrs
	Immune-mediated haemolytic anaemia	1 mg/kg	PO	q 24-48hrs
	Immunosuppression	1.1 mg/kg	PO	q 48hrs
Azithromycin	Susceptible infections	5 mg/kg	PO	q 24 - 48 hrs
	Susceptible infections	80 mg stat	PO	weekly x 3
Azodyl	Probiotic	1 capsule	PO	q 12 - 24 hrs
Aztreonam	Susceptible infections	12-25 mg/kg	IV, IM	q 8 - 12 hrs
Baquiloprim	Coccidiosis	30 mg/kg	PO	q 48hrs x 2
Baytril	Susceptible infections	5.0-20.0 mg/kg	PO, SQ, IM, IV (with caution - may cause blindness)	q 24hrsfor 7 - 10 days
Beclomethasone	Anti-inflammatory	200 mg	Inhalant	as required
Benazepril	Afterload reduction (Renal, CHF)	0.25-0.5 mg/kg	PO	q 24hrs
Benzimidazole	Trypanosomiasis	5 mg/kg	PO	q 24hrs for 4 months
Benzocaine	Local anaesthetic	1-5 ml	SQ	as required
Benzoyl peroxide	Seborrhoea, antibacterial	leave on skin for 10mins		q 3 - 4days for 2 weeks
Betamethasone	Anti-inflammatory	0.1-0.2 mg/kg	PO	q 12 - 24hrs
Bethanechol	Bladder atony, dysautonia, FLUTD	1.25-5.0 mg	PO	q 8- 12hrs
Bisacodyl	Constipation	2-5 mg/cat	PO	q 24hrs as needed
Bismuth subcarbonate	GI tract protectant	0.3-3.0 gm	PO	q 4hrs
	Antidiarrheal, antiemetic	1-3 ml/kg	PO	q 4 - 6hrs
Bleomycin	Chemotherapy	10 µg/m²	IV, SQ	q 24hrs for 4 days, then weekly; max dose 200mg/m²
Bran	Stool softener	1-2 teaspoons/400g food	PO	as needed
Brewer's yeast	B vitamin source	0.2 µg	PO	q 24hrs
Bromhexine hydrochloride	Mucolytic for asthma	2 mg/kg	PO	q 12 hrs for 7-10 days
Bromide	Anticonvulsant	30-60 mg/kg	PO	q 12hrs
Bromocriptine	Cushing's syndrome, false pregnancy, lactation cessation	10-30 µg/kg	PO	q 24hrs for 10 -16 days
Budesonide	Asthma, Irritable bowel disease	1 mg/cat	PO	daily
Bunamidine	Cestodes - Taenia spp, Spirometra spp, Diphyllobothrium spp	20-50 mg/kg	PO	after 3hr fast
Bupivicaine hydrochloride	Local Anaesthetic	0.22-3.0 ml/cat	Epidural	stat
Buprenorphine	Opioid analgesia	0.005-0.01 mg/kg	IV, IM	q 4-8hrs
Buspirone (Buspar)	Behavioural therapy	0.5 - 1.0 mg/kg	PO	q12-24hrs
Busulfan	Chronic myelocytic leukaemia	3-4mg/m2 or 0.1 mg/kg	PO	q 24hrs
Butamisole	Nematodes	2.2mg/kg	SQ	q 21days
Butorphanol	Preanaesthetic	0.05-0.4mg/kg with ACP	IV, IM, SQ
	Antiemetic	0.2-0.6mg/kg	SQ, IM, IV
	Analgesia	0.1-0.8 mg/kg	PO	q 6 - 12hrs
Cabergoline (Dostinex)	Induction of estrus/abortion/pyometra	5 micrograms/kg/day	PO, SQ	q 24 hrs
Calcitriol	Hypoparathyroidism, Hyperparathyroidism (primary), Renal secondary hyperparathyroidism	1.5 - 3.0 ng/kg	PO	q 24hrs
Calcium carbonate	Nutritional supplement	1/2 tsp	PO	daily
	Phosphate binder	60-100 mg/kg	PO	daily
Calcium chloride 10%	Ventricular asystole	1 ml/9kg or 0.1-0.3ml/kg	IV (slowly)	stat
	Hypocalcaemia	1 ml/9kg	IV	stat
Calcium citrate	Calcium replacement, Feline lower urinary tract disease (FLUTD)	10-30 mg/kg	PO	q 8hrs
Calcium EDTA	Lead poisoning	100 mg/kg/day	SQ	daily for 5 days
Calcium gluconate	Ventricular asystole	0.5-1.5 ml/kg	IV (slowly)	as required
	Hypocalcemia, hyperkalemia	0.5-1.5 ml/kg	IV (slowly)	as required
Capstar	Fleas	1 tab	PO	daily as needed
Captan powder 50%	Fungal infections	2 tablespoons/gal water	topically, do not rinse	2-3 x week
Captopril	Vasodilator	2-3 mg/cat	PO	q 8-12hrs
		3-6.25 mg/cat	PO	q 12hrs
Carbenicillin	Susceptible infections	15-30 mg/kg	IV	q 8hrs
Carbenicillin indanyl sodium	Urinary tract infections	10-55 mg/kg	PO	q 8hrs
Carbimazole	Hyperthyroidism	5 mg/cat	PO	q 8 - 12hrs
Carboplatin	Chemotherapy	200 mg/m²	IV	q 4weeks
Carmustine	Chemotherapy	50 mg/m²	IV	q 6weeks
Carprofen (Rimadyl)	Analgesia	1-4 mg/kg	SQ	stat
		0.5-1.0 mg/kg	PO	q 24hrs
Cartrofen (Rimadyl)	Analgesia	1-4 mg/kg	SQ	stat
Cefadroxil (Cefa-drops - cephalosporin)	Susceptible infections	50 mg/cat	PO	q 24hrs for 1-4 weeks
Cefovecin	Susceptible infections	8 mg/kg (0.5 cc)	SQ	q 2 weeks x 3
Cephalexin	Susceptible infections	10-35 mg/kg	PO	q 8 - 12hrs
Cerenia	Anti-emetic	1.0 mg/kg	SQ/PO	q 24 hrs for 4 days, then rest 2 days
Cetacaine	Topical anaesthetic	Use cautiously	Topical	May cause methaemaglobinaemia
Charcoal, activated	Adsorbent for poisonings	1-8g/kg	PO	as needed
Chlorambucil	Chemotherapy, Irritable bowel disease	0.1-0.5mg/kg	PO	q 48-72hrs
	Immune mediated skin diseases (Pemphigus, EGC)	0.1-0.2mg/kg	PO	q 48hrs with prednisolone
Chloramphenicol	Susceptible infections	50mg/cat	PO	q 12hrs
Chlordiazepoxide (Benzodiazepine)	Irritable bowel syndrome	1-2 tabs	PO	q 12hrs
Chlorhexidine 0.5%	Burns	dilute 1:40 with saline	topically	q 24hrs
Chlorothiazide	Diuretic	10-40 mg/kg	PO	q12hrs
	Partial ADH deficiency	20-40 mg/kg	PO	q12hrs
Chlorpheniramine	Antihistamine	1-2 mg/cat	PO	q 8-12hrs
	Excessive grooming	2-4 mg/cat	PO	q 12-24hrs
	Antiemetic	0.5 mg/kg	IM	q 6-8hrs
Chlorpromazine	Vomiting, Pancreatitis	0.2-0.5 mg/kg	IM or SQ	q 6-8hrs
Chlortetracycline hydrochloride	Susceptible infections	25 mg/kg	PO	q 6-8hrs
Cholecalciferol (Vit D)	Hyperparathyroidism (primary) Hypocalcaemia	500-2000 U/kg	PO	q 24hrs
Chondroitin	Arthritis	50 - 100 mg/cat	PO	q 24hrs
Cimetidine	Oesophagitis, gastric ulceration, antiemetic, chronic gastritis	5-15 mg/kg	PO, IV, IM	q 8 -12hrs
	Immunomodulator	10-25 mg/kg	IV, IM, PO	q 12hrs
Ciprofloxacin	not bioavailable in cats
Cisapride (Prepulsid)	constipation, megacolon	0.5-5.0mg/cat	PO	q 12hrs
Cisplatin	Chemotherapy	100 mg/m²	IV	q 4 weeks x 2
Clarithromycin	Mycobacterium spp	50 mg/cat	PO	q 12hrs
Clavulox	Susceptible infections	10-20 mg/kg	PO	q 12hrs
Clindamycin	Anaerobic infections	5-11 mg/kg	PO	q 12hrs
	Stomatitis, Pancreatitis	22 mg/kg	PO	q 24hrs
	Exocrine pancreatic insufficiency	5-10 mg/kg	PO	q 6 - 8hrs
	Enteroepithelial cycle	12.5-50 mg/kg	PO	q 12hrs
Clofazimine	Mycobacterium spp	4-8 mg/kg	PO	q 24hrs for 6 weeks
		50 mg/cat	PO	q 48hrs
Clomipramine	Behaviour modification, inappropriate elimination, obsessive compulsive disorders, aggression	1-5 mg/cat	PO	q 12 - 24hrs
Clonazepam (Benzodiazepine)	Anticonvulsant, behaviour therapy	0.5 mg/kg	PO	q 8-12hrs
Clopidogrel	Aortic thromboembolism, hypertrophic cardiomyopathy	18.75 - 75 mg	PO	q 24 hrs
Clorazepate (Benzodiazepine)	Anxiolytic drug	1-2 mg/kg	PO	q 8 - 12hrs
Clotrimazole	Fungal infections	apply to lesion	topical	q 12hrs
	Fungal infections	60 ml of 1 g/dl of polyethylene glycol intranasal		over 1 hr under general anaesthesia
Cloxacillin	Susceptible infections	20-40 mg/kg	PO, IM, IV	q 4 - 8hrs
Coal tar shampoos	Seborrhoea	Keep in contact with skin for 10 mins	Topically	q 24hrs
Cobalamin	see Vit B12
Cod liver oil		1 teaspoon / 10 kg
Codeine	Pain relief	0.5-4 mg/kg	PO	q 6 - 12hrs
	Antitussive, analgesia	0.1-0.3 mg/kg	PO	q 4 - 6hrs
Colchicine	Antifibrotic	0.01-0.3 mg/kg	PO	q 4 - 6hrs
Colony stimulating factor	Neutropenia	2.5-5.0 mg/kg	SQ	q 24hrs
Convenia	Susceptible infections	8 mg/kg (0.5 cc)	SQ	q 2 weeks x 3
Corticotrophin gel (ACTH)	Response test	pre-ACTH sample 0.5-2.2 IU/kg	IM
Cortisone acetate	Hypoadrenocorticism ( Addison's disease)	1 mg/kg	PO, IM	q 24hrs
Cosequin^®	Osteoarthritis	1 capsule	PO	q 24hrs
Cosyntropin	pre-ACTH sample	0.125 mg/cat	IV
		1-2 mg/kg	PO (with caution)	q 12hrs x 2
Cromolyn sodium 4% (Cromone)	Allergic conjunctivitis		Topically	q 4 - 6hrs
Cyanocobalamin	Vit B₁₂ deficiency	50-1000 µg	PO, IM, SQ	q 24hrs
Cyclizine	Antiemetic	4 mg/kg	IM	q 8hrs
Cyclophosphamide	Chemotherapy	100 mg/m²	IV
	Mammary tumours	100 mg/m²	PO	q 3 weeks with doxorubicin
	Immune-mediated haemolytic anaemia	2 mg/kg (50mg/m²)	PO	q 24hrs for 4 days per week
	Lymphosarcoma, myeloproliferative disorders	50 mg/m²	PO	q 48hrs
	Autoimmune skin diseases	50 mg/m²	PO	q 24hrs 4 days/wk or q 48hrs
	Multiple myeloma	7 mg/kg	PO	once
	FIP	2-4 mg/kg	PO	q 24hrs 4 days a week
	Iritable bowel disease	6.6 mg/kg	PO	q 3days then q 24hrs
		2.2 mg/kg	PO	q 24hrs
	Immunosuppressive therapy	2.2 mg/kg (6.25-12.5 mg/cat)	PO	q 48hrs or q 24hrs for 4 days a week
Cyclosporin	Thrombocytopenia, Pemphigus, sebaceous adenitis	4-6 mg/kg	4hr IV infusion	q 24hrs (avoid extravasation)
		3-7 mg/kg	PO	q 12hrs
		10 mg/kg	PO	q 12hrs
Cyclosporin ophthalmic	Dry eye, Eosinophilic keratitis	1-2% solution	drop in eye	q 12hrs
Cyclothiazide	Diuretic	0.5-1.0 mg/kg	PO	q 24hrs
Cyproheptadine	Appetite stimulant, aortic thromboembolism	1-4 mg/cat	PO	q 12 - 24hrs
Cytarabine	Chemotherapy	30-50 mg/kg	IV, IM, SQ	once a week
		100 mg/m²	IV. IM, SQ	q 24hrs for 4 days then
		20 mg/m²	Intrathecal	q 24hrs for 1 - 5 days
Cythioate	Tick prevention	1.5-3.3 mg/kg	PO (tab)	q 72hrs or 2 x week
		0.22 ml/kg	PO (liquid)	q 72hrs or 2 x week
Dacarbazine	Lymphoreticular neoplasms	200-250 mg/m²	IV	q 24hrs for 5 days, every 21 days
	Soft tissue sarcomas	1000 mg/m²	IV infusion	over 6 - 8hrs, every 21 days
Dactinomycin (Actinomycin-D)	Chemotherapy	0.015 mg/kg	IV	q 24hrs for 3 - 5 days, wait 3 weeks then
		0.7-1.5 mg/m²	IV	weekly
Dalteparin (low MW heparin)	DIC, Thrombosis	70 IU/kg	SQ	q 24hrs
Danazol (Danazolol)	Immune-mediated disorders	5-10 mg/kg	PO	q 12hrs
Dapsone	Mycobacterium spp	1.1 mg/kg	PO	q 12hrs for 4-6 weeks
	Brown recluse spider bite	0.7-1.0 mg/kg	PO	q 8hrs
Decitabine (Dacogen)	Chemotherapy - Feline leukemia, methylation inhibitor	400-800 mg/m²	IV, SQ	q 24hrs x 10
Deferoxamine mesylate	Iron chelator	10 mg/kg	IV, IM, SQ	q 2hrs for 2 doses then q 8hrs for 24 hrs
	Reperfusion (ischaemia) injuries	50 mg/kg	IV	over 5 mins
Demeclocycline	Inappropriate ADH secretion	3-12 mg/kg	PO	q 6 - 12 hrs
Deprenyl (Selegiline)	Hyperadrenocorticism	1-2 mg/kg	PO	q 24hrs
Derm caps	Skin disorders	1 capsule per 9kg	PO	q 24hrs
Desmopressin acetate	Central diabetes insipidus	0.3 µg/kg	IM	q 12 - 24hrs
Desoxycorticosterone acetate	Hypoadrenocorticism	0.2-0.4 mg/kg	conjunctivally	q 24hrs, max 5mg
Desoxycorticosterone pivalate	Addison's disease	25 mg	IM	stat
Dexamethasone	Central oedema, spinal cord trauma, DJD, other CNS trauma	2 mg/kg	IV	then,
		1 mg/kg	IV, SQ	q 8-12hrs, then
		0.1 mg/kg	IV, SQ, PO	q 8-12hrs
	Hydrocephalus	0.25 mg/kg	IV, IM, PO	q 6 - 8hrs
	Shock, anaphylaxis	4 - 6 mg/kg	IV (slowly)
	Immune-mediated disease	0.25-1.25 mg/kg	PO	q 12 - 24hrs
		0.1-0.15 mg/kg	SQ, PO	q 12hrs for 5 - 7 days, then taper dose
	Addison's disease	0.1-0.5 mg/kg	SQ, IV	with mineralocorticoids
	Asthma	1 mg/kg	IV	then
		0.25-1.0 mg/cat	PO	q 8 - 24hrs
Dexchlorpheniramine (Polaramine)	Antihistamine	0.5 - 1.0 mg/cat	PO	q 12 - 24 hrs
Dexrazoxane	Iron chelation for doxorubicin-induced cardiotoxicity	25 mg/kg (ratio of 10-20:1 dexrazoxane : doxorubicin)	IV	15 mins before doxorubicin
Dextran 40	Shock	10-20 ml/kg	IV	q 24hrs
Dextran 70	Volume expander	10-20 ml/kg	IV	q 24hrs to effect
Dextroamphetamine	Narcolepsy	5-10 mg	PO	q 8hrs with imipramine
	Hyperkinesis	0.2-1.3 mg/kg	PO	as needed
Dextromethorphan	Coughing	0.5-2.0 mg/kg	PO, SQ, IV	q 6 - 8 hrs
Dextrose, 50%	Hypoglycaemia, insulin overdose	2 ml/kg	PO
		0.25-1.00 ml/kg	IV
Dextrose, 5%	Hypoglycaemia, insulin overdose	40-50 ml/kg	IV, SQ, IP	as needed
Diazepam (Valium)	Sedation	0.5-2.2 mg/kg	PO	as needed
	Seizures	0.15-0.70 mg/kg or 2-5mg/cat	PO, IV	q 8hrs
	Status epilepticus, certain toxicoses	0.5-1.0 mg/kg	IV	in increments of 5 - 20mg
	Strychnine-induced seizures	2-5 mg/kg	IV	as needed
		0.5 mg/kg	IV
	Reflex dyssynergia (urethral obstruction)	2.5-5.0 mg/cat	PO	q 6 - 8hrs
		0.5 mg/kg	IV
	Urinary disorder in cat	1.25-2.5 mg/cat	PO	q 8 - 12hrs
	Appetite stimulant	0.05-0.4 mg/kg	IV, PO, IM	q 24 - 48hrs
		1 mg/cat	PO	q 24hrs
	Overgrooming	1-2 mg	PO	q 12hrs
		1 mg/kg	PO	q 8 - 12hrs
Dichlorphenamide	Glaucoma	3-5 mg/kg	PO	q 8- 12hrs
Dichlorvos	Parasites - Hookworm, whipworm, roundworm	11-22 mg/kg	PO	repeat in 3 weeks
Dicloxacillin^[1]	Susceptible infections	10-50 mg/kg	PO	q 6 - 8hrs
Dicoumarol	Anticoagulant	5 mg/kg	PO	load, then
		1.3-2.6 mg/kg	PO	oid (monitor response)
Dicyclomine^[2]	Detrusor hyperspasticity or urge incontinence	10 mg/cat	PO	q 6 - 8hrs
Diethylstilboestrol	Feline symmetrical alopecia	0.05-0.1 mg/cat	PO	q 24hrs
Difloxacin (Fluoroquinolone)	Susceptible infections	5-10 mg/kg	PO	q 24hrs
Digoxin	Congestive heart failure	0.005-0.008 mg/kg/day	PO	divided in 12hr doses
Dihydrostreptomycin	Susceptible infections	10-30 mg/kg	IM, SQ	q 12 - 24hrs
Dihydrotachysterol	Milk fever	0.03-0.06 mg/kg	PO	q 24hrs for 3, then
		0.01-0.02 mg/kg	PO	q 24hrs
Diltiazem	Hypertension, Hypertrophic cardiomyopathy, Supraventricular tachycardia	0.5-2.5 mg/kg	PO	q8hrs
Dimenhydrinate	Antihistamine	12.5 mg/cat	PO, IM, IV
Dimercaprol (BAL)	Arsenic toxicosis	2.5-5.0 mg/kg	IM	q 4hrs for 2 days, then q 8hrs for 3 days, then q 12hrs for 10 days
Dimethylsulfoxide (DMSO)	Spinal cord trauma, Amyloidosis	0.5-1 g/kg	IV (10%)	q 6 - 8hrs over 45 min
Diminazine aceturate	Feline babesiosis, Trypanosomiasis	2.0-3.5 mg/kg	IM	Once
		3.5 mg/kg	IM, SQ	q 24hrs for 2 days
Dinoprost	see prostaglandin F2a
Diphenhydramine (Benadryl)	Antihistamine	2-4 mg/kg	PO	q 6 - 8hrs
	Mast cell tumour, antiemetic	2 mg/kg	IM, IV	q 12hrs as needed
	Anaphylaxis, urticaria, angioneurotic oedema	2 mg/kg	IM, IV	q 12hrs as needed
Diphenoxylate HCl	Acute colitis	0.05-0.1 mg/kg	PO	q 12hrs
		0.6-1.2 mg/cat	PO	q 8 - 12hrs
Diphenylthiocarbazone	Thallium toxicosis	50-70 mg/kg	PO	q 8hrs
Diphemanil methylsulphate	Anticholinergic (bronchodilator)	1.8 mg/kg	IM	q 12hrs
Dipyridamole	Antithrombotic	4-10 mg/kg	PO	q 24hrs
		25 mg/kg		q 8hrs (low dose);12 - 24hrs (high dose)
Disodium EDTA	Calcium keratopathy	0.37% solution	topically	lavage cornea for 15 - 20 mins
		1% solution; 1-2 drops	topically	q 12 hrs for several weeks
Dithiazanine iodide	Microfilaricide	6.6-11 mg/kg	PO	q 24 hrs for 7 - 10 days
DL methionine	see methionine
Dobutamine	Positive ionotrope	0.5-2.0 µg/kg/min	IV infusion (caution)	1 min
Docusate sodium or calcium	Stool softener	50 mg/cat	PO	q 12 - 24hrs
	disposable enema	250 mg/12ml glycerin	Rectal	q 24hrs as needed
Dolasetron	Antiemetic	0.6 mg/kg	PO, IV, SQ	q 24hrs
Dopamine HCl	Inotropic agent	2-25 µg/kg (up to 50 µg/kg if severe hypotension or shock)	IV infusion	1 min
	Renal vasodilator, acute renal failure	2-5 µg/kg (low dose)	IV infusion in 5% dextrose/saline	1 min
Doxapram	Respiratory stimulant in neonates	1-5 mg/kg	IV (umbilical vein)	as needed
		1-2 drops	PO	as needed
Doxorubicin (Adriamycin)	Chemotherapy	10-30 mg/m²	IV	q 21 days
Doxycycline (Vibravet)	Susceptible infections	5-10 mg/kg	PO, IV	q 12 - 24hrs
Doxylamine succinate	Antihistamine	1.1-2.2 mg/kg	PO, SQ, IM	q 8 - 12hrs
Edrophonium	Myasthenia gravis diagnosis	2.5 mg/cat	IV	stat
Emetine	Vomiting	3.3 ml/kg, dilute 50:50 with water	PO	stat
Emodepside (Profender)	Anthelmintic	1 x vial	topically	monthly
Enalapril (ACE inhibitor)	Hypertension, Congestive heart failure, Valvular endocardiosis	0.25-0.5 mg/kg	PO	q 12 - 24hrs
Endotoxin antisera	Endotoxemia	408 mg/kg	IV	stat
Enflurane	Gaseous anaesthesia	Induction: 2-3% Maintenance: 1.5-3.0%	intratracheal	as needed
Enilconazole 10%	Nasal aspergillosis	5% solution (1:1 in water)	topically	q 12hrs for 7 - 10 days
		10-20 mg/kg (10% solution: 50:50 in water	instil into nasal sinus	q 12hrs for 10 - 14 days
	Dermatophytes	dilute to 0.2% solution	wash	q 72 - 96hrs for 4 treatments
Enrofloxacin	Susceptible infections	5.0-20.0 mg/kg	PO, SQ, IM, IV (with caution - may cause blindness)	q 24hrs for 7 - 10 days
Epakitin	Phosphate binder for chronic renal disease	1 g/5 kg	PO	q 12hrs
Ephedrine	Bronchodilator, urinary incontinence	2.0-5.0 mg/kg	PO	q 8 - 12hrs
Epinephrine: Use 1:10,000 stock, dilute 1:1000 in 10ml saline	Cardiac arrest	0.2 ml/kg	IV, intratracheal	q 5 - 15 min as needed
	Anaphylaxis, Feline asthma	0.1 ml/kg	SQ, IM, IV	q 5 - 15 min as needed
Epsiprantel	Parasites - Dipylidium spp, Taenia spp	2.5-2.75 mg/kg	PO	stat
Ergocalciferol	Vitamin D	500-2000 IU/kg	PO	q 24hrs
Erythromycin	Susceptible infections	10-22 mg/kg	PO, IV	q 8hrs
Erythropoietin (Eprex 1000)	Anaemia from Kidney disease	50-100 IU/kg	SQ	3 x weekly for 12 weeks then twice weekly (as need to maintain PCV at 35%)
		400 IU/kg	IV, SQ	once a week
Esmolol	Selective B₁ blockade	0.05 mg/kg	slow IV	loading dose, then
		50-200 µg/kg	IV infusion	per min
Estradiol cypionate	mesalliance	125-250 µg/cat	IM	between 40hrs and 5 days post-coitus
Ethacrynic acid	Diuretic, pulmonary oedema	0.2-0.4 mg/kg	IV, IM	q 4 - 12hrs
Ethanol (20%)	ethylene glycol toxicosis	5 ml/kg	IV	q 6hrs for 30hrs, then q 8hrs for 32 hrs
Ethosuximide	Epilepsy	40 mg/kg	PO	load, then
		20 mg/kg	PO
EDTA	anticoagulant, chelation	1 mg/kg	IV	q 2hrs
Etidronate disodium	Hypercalcemia	10 mg/kg	PO	q 2hrs
Etomidate	Anaesthetic induction	0.5-3.0 mg/kg	IV	as needed
	With opioids	0.5-1.0 mg/kg	IV	as needed
Etretinate	Dermatopathy	1-2 mg/kg	PO	q 24hrs
Euthanasia solution	Pentobarbitone sodium	120 mg/kg for first 4.5kg; 60mg/kg thereafter	IV	stat
	with phenytoin	1 ml / 4.5 kg	IV	stat
Famotidine	Gastric antisecretory (H₂ receptor antagonist)	0.5 mg/kg	IM, SQ, PO	q 12 - 24hrs
Famciclovir	Antiviral	62.5 mg/kg	PO	q 12 - 24hrs
Fatty acids (essential)	Atopy, fatty acid deficiency	Derm caps - 1 cap/cat	PO	q 24hrs
Febantel	Antiparasiticide	10 mg/kg per 1mg/kg praziquantel	PO	q 24hrs for 3 days
Feliway	Pheromone	metered dose	topically	ad lib
Fenbendazole	Capillaria aerophilia, Coccidiosis	25-50 mg/kg	PO	q 12hrs for 3-14 days
	Mesocestoides spp	50-100 mg/kg	PO	q 12 - 24hrs for 28 days, repeat in 1 week
Fentanyl (Patches)	Analgesia	0.01 mg/kg	IV, SQ, IM
			transdermal	q 72 - 96hrs
Ferric cyanoferrate	Thallium toxicosis	4-8 mg/kg	PO	q 8hrs
Ferrous sulphate	Anaemia	50-100 mg/cat	PO	q 24hrs
Fitergol (Nicergoline)^[3]	Cognitive disorders	1-5 mg/cat	PO	q 24hrs
Flavoxate	Urinary urge incontinence (Detrusor hyperspasticity)	100-200 mg/cat	PO	q 6 - 8hrs
Florfenicol (Chloramphenicol analogue)	Susceptible infections	22-50 mg/kg	PO, IM, SC	q 12hrs
Fluconazole	Fungistatic / fungicidal (dose related)	2.5-10.0 mg/kg	PO with food	q 12 - 24hrs
	Cryptococcus	50-100 mg/cat	PO with food	q 12 - 24hrs
Flucytosine	Cryptococcus	30-50 mg/kg	PO	q 6 - 8hrs
	Urinary candidiasis	67 mg/kg	PO	q 8hrs
Fludrocortisone acetate (Aldosterone analogue)	Addison's disease	0.1-0.2 mg/cat	PO	q 24hrs
Flumazenil	Hepatic encephalopathy	0.2 mg/cat	IV	as needed
Flumethasone	Anti-inflammatory	0.15-0.3 mg/kg	IV, IM, SQ	q 24hrs
Flunixin meglamine	Anti-inflammatory	0.5-2.2 mg/kg	IV, IM, SQ	stat
Fluoxetine (Prozac)	Behavioural problems (SSRI)	0.5-4 mg/cat	PO	q 24hrs
Flurazepam (Benzodiazepine analogue)	Appetite stimulant	0.2-0.4 mg/kg	PO	q 4 - 7 days
Flurbiprofen (an NSAID - 0.03% solution)	Allergic conjunctivitis	0.2-0.4 mg/kg	Topically	q 8 - 12hrs
Folic acid	Dietary supplement	2.5 mg/cat	PO	q 24hrs
Folinic acid	'Rescue' for sulfonamides	1 mg/kg	PO	q 24hrs
Follicle stimulating hormone (FSH)	Induction of oestrus	500 IU HCG	IV, IM, SQ	q 24hrs for 2 days
Fomepizole (4-Methylpyrazole)	Antifreeze toxicity	20mg/kg	IV	stat
		15mg/kg	IV	q12hrs for 2 days, then
		5mg/kg	IV	as required
Fortekor	Afterload reduction (Renal, CHF)	0.25-0.5 mg/kg	PO	q 24hrs
Foscanart sodium (phosphonoformate)	Susceptible viral infections	13.3 mg/kg	IV, PO	q 8hrs
Furazolidone	Giardia spp	4 mg/kg	PO	q 12hrs for 7-10 days
	Amoebic colitis	2.2 mg/kg	PO	q 8hrs for 7-10 days
	Coccidiosis	8-20 mg/kg	PO	q 24hrs for 5 days
Furosemide	Diuresis	2-4 mg/kg	IV, IM, PO	q 8 - 12hrs as needed
	Hypertension	0.5-2.0 mg/kg	PO	q 12hrs
	Hydrocephalus, brain oedema	1-2 mg/kg	PO	q 12hrs
Gabapentin	Epilepsy (add-on)	10 mg/kg	PO	q 8 - 12hrs
Gamma globulin	Immune-mediated disease	1 g/cat	IV	q 6 - 12hrs
Gentamicin	Susceptible infections	6-8 mg/kg	IM, SQ, IV	q 24hrs
Glimipiride (sulfonylurea)	Non-insulin-dependant diabetes mellitus	1-2 mg/cat	PO	q 24hrs
Glipizide (sulfonylurea)	Non-insulin-dependant diabetes mellitus	0.25-0.5 mg/kg	PO	q 8 - 12hrs
		2.75-7.5 mg/cat	PO	q 8 - 12 hrs (gradual increase in maximum dose as needed based on serum glucose)
Glyburide (sulfonylurea)	Non-insulin-dependant diabetes mellitus	0.2 mg/kg	PO	q 24hrs
		0.625 mg/cat	PO	q 24hrs
Glycerin	Acute glaucoma	1-2 ml/kg of 50% solution	PO	repeated once at 8 hrs
Glyceryl guaiacolate	Muscle relaxation during certain toxicoses	110 mg/kg	IV	as needed
Glyceryl monoacetate	Sodium fluoroacetate toxicosis	0.55 mg/kg hourly to 2-4mg/kg	IM	as needed
Glycopyrrolate	Sinus bradycardia, SA block, AV block	0.005-0.010 mg/kg	IV, IM	as needed
	Hypersialism	0.01 mg/kg	SQ	as needed
	Preanaesthetic	0.01-0.02 mg/kg	SC, IM	stat
Gold sodium thiomalate	Immune-mediated disease	1-5 mg/cat	IM	weekly x 3; 2nd + 3rd week at 2 - 10 mg/cat
Gonadotropin hormone (Folligon)	Anestrus	100 I.U./cat	IM	single treatment
Gonadotropin releasing hormone (Chorulon)	Cystic ovarian syndrome, Ovarian remnant syndrome	25 µg/cat	IM	single treatment
		25 µg/cat	IM	after mating, or on days 2 of oestrus
Granisetron	Chemotherapy-associated emesis	0.1 - 0.5 mg/kg	IV, PO	q 12 - 24hrs
Granulocyte colony stimulating factor	Neutropenia	3-10 µg /kg	SQ	q 12 - 24hrs
Griseofulvin (Grisovin)	Antifungal	10-30 mg/kg	PO	q 24hrs for 4 weeks
Guaifenesin	Tranquiliser	44-88 mg/kg (alone)	IV	stat
		33-88 mg/kg (with thiamylal)	IV	stat
		33-88 mg/kg (with ketamine)	IV	stat
Halofuginone	Coccidiostat, Immunosuppressant	100 µg/kg	PO	q 24 hrs
Haloperidol	Psychogenic alopecia	2 mg/cat	PO	q 12hrs
Halothane	Gaseous anaesthesia	Induction: 3%	Inhalant	stat
		Maintenance: 0.5-1.5%	Inhalant	as needed
Haemoglobin (polymerised bovine)	Blood replacement	10-30 ml/kg	IV	stat
Heparin	Aortic thromboembolism, thrombophlebitis	Initial dose: 100-200 IU/kg	IV	then
		Maintenance dose: 50-100 IU/kg	SQ	q 6 - 8hrs
	Aortic thromboembolism	Induction 1000 IU/kg	IV	then
		Maintenance: 50 IU/kg	SQ	q 8hrs
	Pancreatitis	50-1000 IU/kg	SQ	q 8 - 12hrs
	DIC	75-100 IU/kg	IV, SQ	q 6hrs
	Lipoprotein lipase provocation test	100 IU/kg	IV	test lipids before and 15 mins after heparin
Heparin, LMW	see Dalteparin
Hetacillin	Susceptible infections	10-20 mg/kg	PO	q 8 - 12hrs not associated with feeding
Hetastarch (Hydroxyethyl starch)	Plasma volume expander	10-20 ml/kg	IV	as needed
Human gammaglobulin	Immune-mediated disease	0.5-1.5 g/kg	IV	q 12hrs (infusion)
Hycodan (Hydrocodone)	Antitussive	0.22 mg/kg	PO	q 12hrs
Hyaluronate sodium	Synovitis	3-5 mg/cat	intra-articular	q 7days
Hydralazine	Vasodilator: heart failure	0.5 mg/kg, titrate up to 0.5-0.8 mg/kg (up to 10mg/cat)	PO	q 12hrs
Hydrochlorothiazide	Hypertension	0.5-2.0 mg/kg	PO	q 12 - 24hrs
	Nephrogenic diabetes insipidus	0.5-5.0 mg/kg	PO	q 12hrs
	Hypoglycaemia	2-4 mg/kg	PO	q 12hrs
	Calcium oxalate uroliths	2 mg/kg	PO	q 12hrs
Hydrocortisone	Replacement therapy	0.5-1.0 mg/kg	PO	q 24hrs
	Anti-inflammatory	2.5-5.0 mg/kg	PO	q 12hrs
Hydrocortisone aurate	Hypoadrenocorticism	0.1-0.2 mg/kg	IM	q 8 - 12hrs
	Immune-mediated haemolytic anaemia	2-4 mg/kg	IM	q 12 - 24hrs
Hydrocortisone sodium succinate	Shock	8-150 mg/kg	IV	stat
Hydrogen peroxide (3%)	Emetic	5-10 ml/cat	PO	stat
Hydromorphone	Analgesia	0.05 - 0.1 mg/kg	IM, SQ	every 24 hrs
Hydroxyurea	Primary polycythemiapolycythemia	25-30 mg/kg	PO	q 3days
	Chronic granulocytic leukaemia	0.5 g/m²	PO	q 12hrs for 4-6 weeks, then halve dosage
Hydroxyzine	Antihistamine	5-10 mg/cat	PO	q 12hrs
Hypertonic saline	Shock	2-6 ml/kg	rapid IV infusion	stat
Idarubicin HCl	Antiviral	2.0 mg/kg	PO	q 24hrs for 2 days, then repeat q21 days
Idoxuridine	Ocular herpes viral infection	0.1% solution: 1 drop	topically	q 4 - 6hrs
		0.5% ointment	topically	q 1hr
Imatinib mesylate	Chemotherapy	10 mg/kg	orally	once daily
Imidacloprid	Fleas	100 mg/ml	topically	0.1 cc/kg monthly
Imidocarb	Ehrlichia spp	5 mg/kg	IM	every 14 days x 2
Imidapril	Congestive heart failure and Chronic renal disease	0.5 mg/kg	PO	q 24hrs
Imipenem-cilastin (Broad-spectrum 'Gorilla-cillin')	Susceptible infections	2-10 mg/kg	IM or slow IV	q 6 - 8hrs
Imipramine	Behavioural modification, urinary incontinence	2.5-5.0 mg/cat	PO	q 12hrs
Insulin, glargine	Diabetes mellitus	0.25-5.0 U/kg	SQ	q 12hrs, adjust as needed
Insulin, lente	Diabetes mellitus	0.5 U/kg	SQ	q 12 - 24hrs
Insulin, NHP	Diabetes mellitus	1-3 U/cat	SQ	q 12 - 24hrs
Insulin, PZI	Diabetes mellitus	1-3 U/cat	SQ	q 12 - 24hrs
Insulin, regular	Diabetes mellitus	1-2 U/cat	SQ	q 6 - 8hrs
Insulin, ultralente	Diabetes mellitus	1-3 U/cat	SQ	q 12 - 24hrs
Ipakitine	Chronic renal disease	1 g/cat	PO	q 12 hrs
Interferon a₂, human recombinant	Immunostimulant in non-neoplastic feline leukemia	15-30 U/cat	IM, SQ, PO	q 24hrs on alternate weeks
	FeLV appetite stimulant	1 U/cat	PO	q 24hrs
	FIP (dry)	30 U/cat	PO	q 24hrs on alternate weeks
	FIP(wet)	2000 U/cat	IM	q 24hrs
	Conjunctivitis	10 U/cat	PO	q 24hrs
Interferon-a_2b, human recombinant	Immunostimulation	15-30 U/cat	PO, SQ, IM	q 24hrs for 7 days
Interferon-Ω (Virbagen), feline recombinant	Immunostimulation	1 million U/kg	SQ	q 48hrs, reducing to once weekly if responding
Iodine	Hyperthyroidism	50-100 mg/cat	PO	q 24hrs
Iodide sodium, potassium 20% solution	Hyperthyroidism, Sporothrix spp	20 mg/kg	PO	q 12 - 24hrs
Iopamidol	Myelography	0.25 ml/kg	intrathecal	stat
Ipecac syrup	Emetic	2-6 ml/cat	PO	stat
Ipodate	Hyperthyroidism (short term)	15 mg/kg	PO	q 12hrs
Iron dextran	Anaemia	50 mg/cat	IM	at 18 days of age
Isoflurane	Gaseous anaesthesia	Induction: 5% Maintenance: 1.5-2.5%	Inhalation	stat
Isometheptene	Urethral antispasmodic	0.25-0.5 ml/cat	IM	q 12hrs
		0.5 tab/cat	PO	q 12hrs
Isoniazid	Mycobacterium spp	10-20 mg/kg	PO	q 24hrs
Isopropamide (anticholinergic)	Sinus bradycardia, SA or AV block	0.2-0.4 mg/kg	PO	q 8 - 12hrs
	Antidiarrhoeal, GIT hypermotility	0.2-1.0 mg/kg	PO	q 12hrs
Isoproterenol - isoprenaline (ß₂- agonist)	Bradycardia, AV block, cardiac arrest	0.04-0.08 µg/kg	IV infusion	as needed
	Feline asthma	0.44 mg/kg	PO	q 6 - 12hrs
		0.5ml of 1:200 dilution	Inhalant	q 4hrs x 3
Isosorbide dinitrate	Vasodilator, osmotic diuretic, [megaoesophagus.htm megaoesophagus]	2.5-5.0mg/cat	PO	q 12hrs
Isotretinoin (Vitamin D analogue)	Acne	5 mg/kg	PO	q 24hrs
Itraconazole	Fungal infections or generalised dermatomycosis	5-10 mg/kg	PO	q 12 - 24hrs
Ivermectin	Heartworm disease prophylaxis	24 µg/kg	PO	once monthly
	Microfilaricidal	50 µg/kg	PO	stat
	Endoparasiticidal	200-400 µg/kg	IM, SQ, PO	weekly
	Cheyletiella spp, Notoedres spp	200-400 µg/kg	SQ	stat
Jenotone (Aminopropazine fumarate)	Urinary tract obstruction	2 mg/kg	IM, SQ	q 12hrs
Kanamycin	Susceptible infections	10-15 mg/kg	IV, IM, SQ	q 12hrs
	GI tract bacterial overgrowth	10-12 mg/kg	PO	q 8 - 12hrs
Kaolin / pectin	GI tract protectant	1-2 ml/kg	PO	q 2 - 6hrs
Ketamine (NMDA-receptor antagonist)	Anaesthesia (with Xylazine)	7-11 mg/kg (0.2-0.5ml)	IV	stat
	Sedation (with diazepam)	5.5-10.0 mg/kg (0.3-0.5ml)	IV	stat
Ketoconazole	Systemic and cutaneous mycoses, Sporothrix spp	5.0-10.0 mg/kg	PO	q 12 - 24hrs
	Fungal infections, CNS mycoses	15-20 mg/kg	PO	q 12hrs
Ketoprofen (NSAID)	Anti-inflammatory	0.5-1.0 mg/kg	PO, IM, SQ	q 24hrs
L-asparaginase (Chemotherapeutic agent)	Lymphosarcoma	10,000 U/m²	IV	weekly as part of a protocol
Lactated Ringer's solution	Rehydration	40-50 ml/kg	IV	q 24hrs
Lactilol	Stool softener, hepatic encephalopathy	250 ml/cat	PO	q 12hrs
Lactoferrin	FIV stomatitis	40 mg/kg	Topical	q 24hrs
Lactulose	Megacolon, Hepatic encephalopathy	2.5-5.0 ml/cat	PO	q 8 - 12 hrs
		5-10 ml diluted in water (1:3)	Rectal	stat
	Stool softener	1 ml/cat	PO	q 8hrs to effect
Lamisil (Terbinafine)	Fungal infections	20 - 30 mg/kg	PO	q 24hrs for 4 - 10 weeks
Lenperone	Opioid preanesthetic	0.22-0.88 mg/kg	IM, IV	stat
Leucovorin	Methotrexate toxicity	3 mg/m²	IM	within 3hrs of poisoning
	Pyrimethamine antidote	1 mg/kg	PO	stat
Levallorphan (1st generation opiate antagonist)	Opioid toxicity/overdose	0.02-0.20 mg/kg	IV	as needed
Levamisole	Heartworm disease	10 mg/kg	PO	q 24hrs for 7 days
	Heartworm disease, Filaroides, Lungworm	25 mg/kg	PO	q 48hrs for 14 days
	Hookworms	10 mg/kg	PO	q 24hrs for 2 days
	Immune stimulant	4.4 mg/kg	PO	stat
Levarterenol (Norepinephrine)	Positive ionotrope	0.05-0.3 µg/kg	IV	q1 min
Levetiracetam	Seizures (add-on)	15-20 mg/kg	PO	q 8 - 12hrs
	Cognitive disorders	15-20 mg/kg	PO	q 8 - 12hrs
Levodopa (L-DOPA)	Hepatic encephalopathy	6.8 mg/kg initially, then 1.4mg/kg	PO	q 6hrs
Thyroxine (Synthetic T₄)	Hypothyroidism (very rare in cats)	10-30 µg/kg	PO	q 12hrs
Lidocaine (Xylocaine)	Ventricular arrhythmias	0.25-1.0 mg/kg	IV	then
		10-40 µg/kg	IV	per min
	Epidural	4.4 mg/kg	epidural	stat
Lime sulphur	Sarcoptic mange	1:40 dilution	Topically	weekly for 6 weeks
Lime water	Alkaline gastric lavage	5 ml/kg	PO	stat
Lincomycin	Susceptible infections	11-33 mg/kg	PO, IV, IM	q 12 - 24hrs
Liothyronine (T3)	Hypothyroidism	4.4 µg/kg	PO	q 8 - 12hrs
Lisinopril (ACE inhibitor)	Afterload reduction (vasodilator)	0.25-5.0 mg/kg	PO	q 24hrs
Lobaplatin	Chemotherapy	35 mg/m²	IV	q 3hrs
Lomustine	Chemotherapy	100-150 mg/m²	PO	q 6 weeks (subsequent dose based on WBC)
Loperimide	Antidiarrhoeal	0.1-0.3 mg/kg	PO	q 12 -2 4hrs
Lufenuron	Immunomodulator	15-30 mg/kg	PO	q 24hrs with meal for 30 days
	Flea control	10 mg/kg	SQ
	Antifungal [fungal%20diseases.htm (ringworm)]	80 mg/kg	PO	repeat in 2 weeks
Lufenuron / milbemycin	Heartworm disease prevention	1 tablet for appropriate size	PO	monthly
Luteinizing hormone (LH)	Stimulate ovulation	50 IU/cat	IM	after mating
L-lysine	Eosinophilic keratitis / Herpes rhinitis	250-500 mg	PO	q 12 - 24hrs
Lysine-8-vasopressin	Central diabetes insipidus	1-2 sprays	conjunctival	q 8 - 24hrs
Magnesium citrate	Laxative	2-4 ml/kg	PO	stat
Magnesium hydroxide	Antacid	5-10 ml/cat	PO	q 8 - 24hrs
	Cathartic	2-6 ml/cat	PO	q 24hrs
Magnesium salts	Laxative	2-5 g/cat	PO	q 24hrs
Magnesium sulphate (25%)	Hypomagnesemia	5-15 mmol/cat	IM, IV	over 1 - 2 hrs
Mannitol 5-20%	Oliguric renal failure	0.25-1.0 g/kg	IV over 15-60 min	q 4 - 6hrs to maintain urine flow
	Glaucoma	1-3 mg/kg	IV over 15-20 min
	CNS oedema	1.5 mg/kg	IV	stat
Marbofloxacin (Fluoroquinolone)	Susceptible infections	2.75-5.5 mg/kg	PO	q 24hrs
Maropitant (Cerenia ™ )	Anti-emetic	1.0 mg/kg	SQ/PO	q 24 hrs for 4 days, then rest 2 days
Mebendazole	Parasites	22 mg/kg	PO	q 24hrs for 3 days
Meclizine (antihistamine)	Motion sickness, nausea	12.5 mg/cat	PO	q 24hrs, 1 hr before driving
Medetomidine	Chemical restraint, sedation, analgesia, muscle relaxant	50-150 µg/kg	SQ, IM	stat
Medium chain triglycerides	Chylothorax	14 ml/cat with each meal	PO	as needed
	Primary lymphangiectasia, Exocrine pancreatic insufficiency	14 ml/cat	PO	q 6 - 8hrs
Medroxyprogesterone acetate (MPA-50; 50mg/ml)	Aggression, Oestrus postponement, prevent abortion	1-2 mg/kg	IM	once weekly, stop 7-10 days before parturition
	Urine marking, anxiety, intraspecies aggression, skin conditions	10-20 mg/kg	SQ	as needed, up to 3 injections per year
	Skin conditions	50-100 mg/cat	SQ, IM	q 3 - 6mths as needed
	Behavioural disorders	100 mg/cat	IM	then
		30-50 mg/cat		monthly
Megestrol acetate (Ovarid)	Gingivitis	2.5-5.0 mg/cat	PO	q 24hrs for 10 days, then q48hrs for 5 treatments, then as needed
	Urethritis	2.5-5.0mg/cat	PO	q 24 - 48hrs for 14-21 days until remission, then 1-2 weeks
	Miliary dermatitis, eosinophilic granuloma complex	2.5 mg/cat	PO	q 24hrs for 10 days then q48hrs
	Eosinophilic granuloma complex	0.5 mg/kg/day	PO	for 7-14 days
	Eosinophilic ulcers	5-10 mg/cat	PO	q 48hrs for 10 - 14 treatments then q 2nd week
	Oestrus prevention	2.5-5.0 mg/cat	PO	q 7 days
	Asthma	5 mg/cat	PO	q 24hrs for 4 months, then weekly for 4 weeks
	Chemical contraception	5.0 mg/cat	PO	q 24hrs for 3 days, then weekly as needed
Meglumine antimonate	Leishmaniasis	5-30 ml/cat	IV, IM, IP	q 48 - 72hrs
Melatonin	Anterior uveitis	0.01 - 1.0 mg	PO	q 24hrs
	Oestrus suppression	30 mg	PO	q 24hrs for 30 days
Meloxicam	Antiinflammatory	0.01 - 0.03 mg/kg	PO	q 24hrs as needed
Melphalan (nitrogen mustard alkylating agent)	Multiple myeloma	0.05 mg/kg	PO	q 24hrs for 2 weeks, then q48hrs
	Ovarian carcinoma, multiple myeloma, lymphoma, osteosarcoma, mammary or pulmonary neoplasms, FIP, Feline leukemia	2 mg/m²	PO	q 48hrs
Mepiridine (pethidine)	Sedation	1-5 mg/kg	IM	q 2 - 4hrs
Mepivacaine	Local analgesia	1-5 ml of 2% solution	SQ	as needed
6-Mercaptopurine	Chronic myelocytic leukaemia, Lymphoma	2 mg/kg	PO	q 24hrs
Meropenem	Susceptible infections	20 mg/kg	IV	q 8hrs
	Meningitis	40 mg/kg	IV	q 8hrs
Mesna	Haemorrhagic cystitis associated with cyclophosphamide	40% of cyclophosphamide dose	PO, IV, IM, SQ	q 3hrs x 6 at time of cyclophosphamide treatment, follow with repeat dose (24 hr infusion)
Metamucil	Laxative	2-4 g/cat	in moistened food	q 12 - 24hrs
Metaproterenol	Bronchodilation	0.325-0.65 mg/kg	PO	q 4 - 6hrs
Metaraminol (a₁-agonist)	Vascular support during shock	0.01-0.1 mg/kg	IV slowly	stat
http://en.wikipedia.org/wiki/Metformin Metformin]	Hyperglycaemia (non-insulin-dependant diabetes mellitus)	2 mg/kg	PO	q 12hrs
Methazolamide	Glaucoma	1-2 mg/kg	PO	q 12hrs
Methenamine hippurate	Urinary antiseptic	250 mg/cat	PO	q 12hrs (use with extreme caution)
Methicillin (ß-lactam antibiotic)	Susceptible infections	20 mg/kg	IM, IV	q 6hrs
Methimazole	Hyperthyroidism	5 mg/cat (induction)	PO	q 8hrs, followed by
		2.5-5.0 mg/cat	PO	q 8 - 12hrs
(DL) Methionine (essential AA)	Urinary acidifier	0.2-1.5 g/cat (Adult cats only)	PO	q 24hrs
Methocarbamol (guaifenesin-analogue)	Muscle relaxation	20-66 mg/kg	PO	q 8 - 12hrs
	Relief of moderate conditions	44 mg/kg	IV
	Controlling effects of strychnine and tetanus	55-220 mg/kg; give 1/2 dose rapidly until relaxation occurs and continue at 20-66 mg/kg (not to exceed 330 mg/kg/day)	IV	as needed
Methohexital (thiopentone analogue)	Anaesthesia induction	2.5% solution: 11 mg/kg	IV	stat
Methotrexate sodium	Chemotherapy	2.5 mg/m²	PO	q 24hrs or 2 - 3 x weekly, in a protocol on day 14 with 5 mg prednisolone PO q 12hrs
	Carcinomas, sarcomas	10-15 mg/m²	PO	q 1 - 3 weeks
Methoxamine (a₁-agonist)	Vasopressor: cardiac arrest, shock	200-250 µg/kg or 40-80 µg/kg	IM	stat
Methoxyflurane	Inhalation anaesthesia	Induction: 3%, Maintenance: 0.5-1.5%	Inhalation	stat
Methscopolamine bromide	Anti-emetic	0.3-1.0 mg/kg	PO	q 8hrs (use cautiously)
Methylcellulose	Laxative	1.0-1.5 g/cat	PO	as needed
Methylene blue 0.1%	Indicator dye	3 mg / 250 ml 0.9% NaCl	IV over 30-40 min
	Antidote	1-1.5 mg/kg	IV	stat
Methylprednisolone	Antiinflammatory	0.5-1.0 mg/kg	PO	q 12hrs
Methylprednisolone acetate	sinophilic ulcers, linear granulomas	10-40 mg/cat	SQ, IM, intralesional	q 2 weeks x 2 - 6 treatments
	Asthma	1-2 mg/kg	IM	q 7 days
	Others	5.5 mg/kg	SQ, IM	1 - 24 weeks
Methylprednisolone sodium succinate	Spinal trauma	15-30 mg/kg	IV	q 2hrs, then q 6hrs for 2 days, then taper dose over 5 - 7 days
4-Methylpyrazole	Antifreeze toxicity	20 mg/kg	IV	stat
		15 mg/kg	IV	q 12hrs for 2 days, then
		5 mg/kg	IV
Methyltestosterone	Anabolic steroid	1-2 mg/kg	PO	q 24hrs
	Testosterone-responsive dermatoses	1-2.5 mg/cat	PO	q 48hrs
Metoclopramide	Gastric motility disorders, antiemetic	0.2-0.5 mg/kg	PO, IM, SQ	q 8hrs
		1.0-2.0 mg/kg	IV	q 24hrs
	Gastric reflux	0.2-0.4 mg/kg	PO	q 8hrs, 30 mins before meals
	Feline dysautonomia	0.3 mg/kg	PO	q 8hrs
Metoprolol (ß₁-agonist)	Atrial fibrillation, hypertrophic cardiomyopathy	2-15 mg/cat	PO	q 8hrs
		12.5-25.0 mg/cat	PO	q 12hrs
Metronidazole	Colitis, Coccidiosis, Tritrichomoniasis, anaerobic infections	10-25 mg/kg	PO	q 24hrs for 7 - 14 days
	Gingivitis	50mg/kg	PO	q 24hrs
Metyrapone	Cushing's syndrome	65 mg/kg	PO	q 12 hrs
Mirtazepine	Antiemetic	3mg/cat	PO	q 3days
Misoprostol (synthetic PGE₁)	Mucosal protectant	3-5 µg/kg	PO	q 12hrs as required
Miconazole	Fungal infections	1-3 cm	topically	q 24hrs for 2 - 4 weeks
Midazolam	Preanaesthetic, sedation,	0.06-0.22 mg/kg	IM, IV	stat
	Control of seizures	0.2-0.5 mg/kg	IV	stat
Milbemax	Heartworm and intestinal worm prophylaxis	0.5-2.0 mg/kg	PO	monthly
Milk thistle (silymarin)	Free radical scavenger	50-250 mg/kg	PO	q 12hrs
Mineral oil	Laxative	5-10 ml/cat	PO, per rectum	q 12hrs
Minocycline (tetracycline antibiotic)	Susceptible infections	5-15 mg/kg	PO	q 12hrs
Mithramycin	Hypercalcaemia, testicular cancer, malignancies	0.25-0.50 µg/kg	IV	q 24hrs x 2
Mitotane (o,p-DDD)	Pituitary-dependant hyperadrenocorticism	25 mg/kg	PO	q 7 days (maintenance)
		75-100 mg/kg/week PO
Mitoxantrone	Anticancer chemotherapy	6.0-6.5 mg/m²	IV	q 3-4 weeks x 4 - 6
Morphine	Antitussive, analgesia	0.05-0.1 mg/kg	SQ, IM	q 4 - 6hrs
Moxifloxacin	Mycobacterium spp, Bartonella spp	5.0 mg/kg	PO	q 24 hours
Mycobacterial cell wall extract	Immunostimulation	1.5 ml	IV, deep IM	q 24hrs x 1
Nadolol (ß_1/2- antagonist)	Hypertension	0.25-0.5 mg/kg	PO	q 12hrs
Nafcillin (ß-lactam antibiotic)	Resistant staphylococcal infections	10 mg/kg	PO, IM	q 6hrs
Nalbuphine hydrochloride (synthetic opioid)	Analgesia	0.75-1.5 mg/kg	IV	q 6 - 8hrs
Nalorphine	Opioid antagonist	0.1 mg/kg	IV	stat
Naloxone HCl	stereotypic behaviour	20 mg	SQ
	Shock	2 mg/kg	IV	q 1hr
	Opioid antagonist	0.01-0.04 mg/kg	IV	to effect, repeat as needed
Naltrexone (Trexan)	Behavioural problems, lick granuloma	2.2 mg/kg	PO	q 12 - 24hrs
Nandrolone decanoate	Anaemia	10-50 mg/cat	IM	weekly
Natamycin (Pimaracin)	Ocular fungal infections		topically	q 3 - 8hrs
N-acetylcysteine	see Acetylcysteine
Neodarbazine	Antiemetic	4.5-9.0 mg/kg	PO	q 12hrs
Neomycin	Susceptible infections	7 mg/kg	IM, IV, SC	q 24hrs (nephrotoxic)
	Hepatic encephalopathy	10-20 mg/kg	per rectum	q 6hrs
Neostigmine	Diagnostic aid for myasthenia gravis	20 µg/kg with 0.04 mg/kg of atropine	IV	stat
		2 mg/kg/day	PO	q 24hrs, divided doses
Niacin (Niacinamide)	Hypertriglyceridemia	50-100 mg/day	PO	q 24hrs
	Vacor toxicosis	500-1000 mg	IM	stat, then
		200 mg	PO	q 24hrs for 2 weeks
Nicergoline^[3]	Cognitive disorders	1-5 mg/cat	PO	q 24hrs	Nikethamide	Antidote for CNS-depressant drugs	7.8-31.2 mg/kg	IV, IM, SQ	stat, then as needed
Nitenpyram	Fleas	1 tab	PO	daily as needed
Nitrofurantoin	Urinary tract infection	2.5-4.0 mg/kg	PO	q 6 - 8hrs
	Prophylactic dose	4 mg/kg	PO	q 24hrs
Nitroglycerin 2% ointment	Vasodilator for pre-load reduction	1/8-1/4 inch (0.3-0.6cm)	cutaneously	q 6 - 8hrs
Nitroprusside (vasodilator)	Acute CHF	0.5-10 µg/kg	IV	q 1 min
Norepinephrine bitartrate	Positive ionotrope	0.05-0.3 µg/kg	IV	q 1 min
Nortriptyline (tricyclic antidepressant - noradrenaline reuptake inhibitor)	Behaviour disorders	0.5-2.0 mg/kg	PO	q 12 - 24hrs
Novobiocin	Susceptible infections	10 mg/kg	PO	q 8hrs
Nystatin	Susceptible infections	100,000 IU	PO	q 8hrs
Octreotide (Sandostatin)^[4]	Chylothorax, Acromegaly	0.1 mg	SQ	q 8hrs
Ofloxacin (fluoroquinolone)	Susceptible infections	2.5-10.0 mg/kg	PO	q 12hrs
Olsalazine sodium	Inflammatory bowel disease	10-20mg/kg	PO	q 12 - 24hrs
Omega fatty acids	see Derm caps
Omeprazole (Losec)	Gastritis, gastric ulceration	5 mg/cat	PO	q 24hrs
Ondansetron - 5-HT₃ receptor antagonists	Antiemetic	0.5-1.0 mg/kg	PO	q 24hrs
Orbifloxacin	Susceptible infections	2.5-7.5 mg/kg	PO	q 24hrs
Ovarid	(see Megestrol acetate)
Oxacillin	Susceptible infections	22-40 mg/kg	PO	q 8hrs
Oxazepam	Appetite stimulant	2.0-2.5 mg/cat	PO	q 12hrs
Oxtriphylline	Bronchodilator	6 mg/kg	PO	q 8 -12hrs
		10-15 mg/cat	PO	q 6 - 8hrs
Oxybutynin (anticholinergic)	Detrusor hyperspasticity	0.5 mg/cat	PO	q 8 - 12hrs
Oxymetholone	Anabolic agent	1 mg/kg	PO	q 12 - 24hrs
Oxymorphone	Preanaesthetic	0.1-0.2 mg/kg	IM, IV	with ACP or atropine
Oxytetracycline	Susceptible infections	55-82.5 mg/kg	PO	q 8hrs
	Haemobartonella	20-40 mg/kg	PO	q 8hrs for 3 weeks
Oxytocin	Acute metritis	0.5-1.0 IU/kg	IV, IM, SQ	q 2hrs for max of 3 doses
Paclitaxel (mitotic inhibitor)	Chemotherapy	5 mg/kg	IV	pre-treat for anaphylaxis
Pancreatic enzymes	Exocrine pancreatic insufficiency	1-2 tablets, 1-2 teaspoons	PO	20 mins prior to food, bid
Pancuronium bromide	Paralytic agent for controlled anaesthesia	0.044-0.11 mg/kg	IV	stat
Paregoric	Antidiarrhoeal	0.05-0.06 mg/kg	PO	q 8 - 12hrs
Paromomycin (aminosidine)	Cryptosporidium spp	125-165 mg/kg	PO	q 12hrs for 5 days
Paroxetine (SSRI)	Behaviour modification	1.25-2.5 mg/cat	PO	q 24hrs
Parvaquone	Toxoplasmosis	10-30 mg/kg	IM	q 24hrs
D- penicillamine	Progressive hepatitis	10-15 mg/kg	PO	q 12hrs
Penicillin G	Susceptible infections	20-30 mg/kg	PO	q 6 - 8hrs
Pentazocine	Analgesia	2.2-3.3 mg/kg	IV, IM, SQ	q 4hrs
Pentobarbital	General anaesthesia	25-30 mg/kg	IV	to effect
	Status epilepticus	5-15 mg/kg	IV	to effect
	Sedation	2-4 mg/kg	PO	q 6hrs
Pentosan polysuphate	Disease modifying agent, arthritis	3 mg/kg	IM, SQ	q 7 days
Pentoxifylline (phosphodiesterase antagonist)	Dermatomyositis	100 mg/cat	PO	q 8 - 12hrs
	Autoimmune skin diseases	10-15 mg/kg	PO	q 24hrs
Periactin	Appetite stimulant	1-4 mg/cat	PO	q 12 - 24hrs
Petrolatum, white	Laxative	1-5 ml/cat	PO	q 24hrs
Phenamidine isethionate	Babesiosis	7.5 mg/kg	IM, SQ	q 24hrs x 2
Phenobarbital	Status epilepticus	2.5-5 mg/kg	PO, IM, IV	q 12hrs
Phenoxybenzamine HCl (a-adrenergic antagonist)	Acute hypertension from Pheochromocytoma	0.5 mg/kg	PO	q 12hrs
	Detrusor areflexia	2.5-10 mg/cat	PO	q 8 - 12hrs
	Relaxation of urinary sphincter	0.5 mg/kg	IV	stat
	Endotoxemia	2.5-10.0 mg/cat	PO	q 24hrs
Phentolamine (a-adrenergic antagonist)	Hypertension from Pheochromocytoma	0.02-0.1 mg/kg	IV	stat
Phenylephrine (a-adrenergic agonist)	Vasopressor, decongestant, mydriatic	0.15 mg/kg	IV	as needed
Phenylpropanolamine	Urethral sphincter incompetence	1.5-2.0 mg/kg	PO	q 8hrs
Phenytoin	Seizures, ventricular arrhythmias	2-3 mg/kg	PO	q 24hrs
Phosphate (K or Na)	Hypophosphatemia	4.5 mg/dl serum phosphate	IV	over 6 hrs
Physostigmine (Syrup)	Myasthenia gravis, Glaucoma, magic-mushroom intoxication	0.25-5.0 mg/cat	IM	q 12hrs
Physostigmine (0.5%)	Feline dysautonomia	apply 1/8 inch	topically	q 8hrs
Phytomenadione	See Vitamin K1
Pilocarpine 1% ophthalmic	Dysautonomia, glaucoma	1 drop	topically	q 6hrs
Pimaricin (Pimaracin)	Ocular fungal infections	1 drop	topically	q 3 - 8hrs
Piperacillin sodium	Susceptible infections	25-50 mg/kg	IV, IM	q 8 - 12hrs
Piperacillin-tazobactum	Susceptible infections	25-50 mg/kg	IV	q 6 - 8hrs
Piperazine	Helminths	44-66 mg/kg	PO	repeat in 3 weeks
Piroxicam (NSAID, non-selective COX inhibitor)	Analgesia, Neoplasia	0.3 mg/kg	PO	q 24 - 72hrs
http://en.wikipedia.org/wiki/Plicamycin Plicamycin]	Hypercalcemia, testicular cancer, malignancies	0.25-0.50 µg/kg	IV	q 24hrs x 2
Polyethylene glycol	Lubricant, intestinal cathartic	25 ml/kg	PO	then repeat in 2-4 hrs before GI exam
Polyethylene glycol electrolyte solution	Electrolyte replacement	25 ml/kg	PO	q 2 - 4hrs
Polymixin B	Sepsis	1-2 mg/kg	IV	stat
Polysulfated glycosaminoglycans	Degenerative joint disease	2-5 mg/kg	IM	q 3 - 5days
Posaconazole	Aspergillosis	2.5 - 3.75 mg/kg	PO	q 12 hrs
Potassium chloride	Potassium supplementation	0.10-0.25 ml/kg	PO	q 8hrs
	Hypokalemia	0.5 mEq/kg	IV	not to exceed 0.5 mEq/kg/hr
		1-3 mEq	PO. IV	q 24hrs
		10-40 mEq/500 ml of fluid, depending on serum potassium	IV, SQ	stat
Potassium citrate	Urolithiasis	50-75 mg/kg	PO	q 12hrs
Potassium gluconate	Hypokalemic polymyopathy	5-8 mEq/cat	PO	q 12 - 24hrs
Potassium iodide	Sporothrix spp, pythiosis	30-100 mg/cat	PO	q 24hrs for 10-14 days
Potassium permanganate (1:2000)	Strychnine toxicosis	5 ml/kg in gastric lavage	PO	stat
Potassium phosphate	see Phosphate
Povidone-iodine	Burns	Apply light coating	Topically	q 12 - 24hrs
Pradofloxacin (Fluoroquinolone)	Broad-spectrum antimicrobial	5 - 10 mg/kg	PO, SQ	q 24 hrs for 7 days
Pralidoxime chloride (2-PAM)	Organophosphate toxicosis	20 mg/kg	IV, IM, SQ	q 12hrs
Praziquantel	Dipylidium spp	5 mg/kg	PO	stat
	Platynosomum spp, Paragonimus spp	25-30 mg/kg	PO	q 24 hrs for 5-10 days
Prazosin (a₁-adrenergic antagonist)	After load reductions	0.5-2.0 mg/cat	PO	q 8 - 12hrs
	Urethral obstruction	0.5-2.0 mg/cat (0.07mg/kg)	PO	q 8 - 12hrs
Prednisolone	Eosinophilic ulcers, plasma cell gingivitis	1-2 mg/kg	PO	q 24hrs (each evening)
	Plasmacytic lymphocytic enteritis	1-2 mg/kg	PO	q 12hrs, then taper dose weekly
	Urethritis, persistent hematuria	2.5-5.0 mg/kg	PO	q 24 - 48hrs
	Anti-inflammatory	2.2 mg/kg	PO	q 12 - 24hrs
	Hypoadrenocorticism	1 mg/kg	PO	q 12hrs
	Chronic therapy	2-4 mg/kg	PO	q 48hrs
	Immune-mediated skin diseases	1.1-2.2 mg/kg	PO	q 12hrs until remission, then taper
	FIP	4 mg/kg	PO	q 24hrs with cyclophosphamide
	Allergy	1 mg/kg	PO, IM	q 12hrs
	Immunosuppression	3 mg/kg	PO	q 12hrs
	Lymphosarcoma, myeloproliferative disorders	1 mg/kg	PO	q 24hrs
	Multiple myeloma	0.5 mg/kg	PO	q 24hrs
Prednisolone acetate	Hypoadrenocorticism	0.1-0.2 mg/kg	IM	q 12hrs
Prednisolone sodium phosphate	Shock	15 mg/kg	IV	q 4 - 6hrs
Prednisolone sodium succinate	Allergic bronchitis, asthma	15-30 mg/kg	IV, IM	to effective dose
	Shock	15-30 mg/kg	IV	q 4 - 6hrs
	CNS trauma	15-30 mg/kg	IV	then taper to effective dose
Pregabalin	Epilepsy	5 -10 mg/kg	PO	q 12 hrs
Prilium	Congestive heart failure and Chronic renal disease	150 mg syrup	PO	0.5ml q 24hrs
Primaquine	Feline babesiosis	0.5 mg/kg	PO, IM	stat
Procainamide	Ventricular arrhythmias	62.5 mg/cat	PO	q 6hrs
Prochlorperazine	Antiemetic	0.1 mg/kg	IM	q 6hrs
		0.5 mg/kg	PO	q 6 - 8hrs
Promazine hydrochloride	Preanaesthetic	2.2-6.6 mg/kg	IV	stat
	Antiemetic	1-2 mg/kg	IM, IV	q 4 - 6hrs
Promethazine HCl	Antihistamine, antiemetic	0.2-0.4 mg/kg	IV, IM, PO	q 6 - 8hrs
Propantheline bromide	Acute colitis, irritable bowel syndrome, antiemetic	0.22-0.25 mg/kg	PO	q 8hrs up to 3 days
	Detrusor hyperspasticity, urge incontinence	0.2 mg/kg	PO	q 6 - 8hrs
Propriomazine	Sedation	1.1-4.4 mg/kg	IV, IM	q 12 - 24hrs
Propionibacterium acnes	Immunostimulation, [feline%20leukemia.htm FeLV associated disease], retrovirus infection	15 µg/kg	IV	biweekly for 2 - 3 weeks
Propofol	General anaesthesia, status epilepticus	Induction: 6-8 mg/kg	IV	stat
		Induction: 2.5-4.0 mg/kg	IV	with premedication
		Maintenance: 0.51 mg/kg	IV	q min
Propranolol (ß-adrenergic antagonist)	Ventricular hypertrophy, aortic stenosis, HCM	0.4-1.2 mg/kg	PO	q 8 - 12hrs
	Ventricular arrhythmias	0.02-0.06 mg/kg	IV	over 2-3 min; q 8hrs
		0.25-0.5 mg	IV	followed by
		2.5-5.0 mg	PO	q 8hrs
	hypertrophic cardiomyopathy, valvular insufficiency	2.5 mg/cat	PO	q 8 - 12hrs
	Hypertension	2.5-5.0 mg/cat	PO	q 8 - 12hrs
	Tachyarrhythmias from endocrinopathies	2.5-5.0 mg	PO	q 8 - 12hrs
Propylthiouracil (PTU)	Hyperthyroidism	10 mg/kg	PO	q 8hrs
		50 mg/cat	PO	q 8 - 12hrs
Prostaglandin F2 alpha	Pyometra, Cystic endometrial hyperplasia	0.10-0.25 mg/kg	SQ	q 24hrs for 3-5 days
	Abortion	0.5-1.0 mg/kg; 40 days post-conception	SQ	2 injections 24 hrs apart
Protamine sulphate	Heparin antagonist	1.0-1.5 mg for every 100 IU heparin	IV	stat
Pseudoephedrine	Nasal decongestant	15-30 mg/cat	PO	q 8 - 12hrs
	Urinary incontinence	0.2-0.4 mg/kg	PO	q 8 - 12hrs
Psyllium	Bulk laxative	1-3 tsp	PO	q 8 - 12hrs
Pyrantel pamoate	Roundworm, hookworm	10 mg/kg	PO	repeat in 2 weeks
Pyridostigmine bromide	Myasthenia gravis(acquired)	1-5 mg	PO	stat
		0.25 mg/kg	PO	q 24hrs
	Antidote (curariform)	0.15-0.30 mg/kg	IM, IV
Pyrilamine maleate	Antihistamine	12.5-25.0 mg/cat	PO	q 6hrs
Pyrimethamine	Malaria, Neosporosis	0.25-1.0 mg/kg	PO	q 24hrs
	Toxoplasma	0.5-2.0 mg/kg	PO	q 12hrs for 14 - 28days
	Enteroepithelial cycle	2 mg/kg	PO	q 24hrs for 14 - 28 days
Quinacrine	Giardia spp, Coccidiosis	11 mg/kg	PO	q 24hrs for 5 days
Ranitidine (Zantac)	H-2 receptor antagonist for use in gastritis, GI tract ulceration	0.5 mg/kg	IV, PO, SQ	q 12hrs
	Hypergastrinemia associated with chronic renal insufficiency	3.5 mg/kg	PO	q 12hrs
Retinol (Vit A)	Dermatological lesions	625-800 IU/kg	PO	q 24hrs
Ribavirin	Susceptible viral infections	11 mg/kg	PO, IM, IV	q 24hrs for 7 days
Riboflavin (Vit B12)	Bartonellosis (with doxycycline)	5-10 mg/kg	PO	q 24hrs for 14days
Rifampicin	Susceptible infections	10-20 mg/kg	PO	q 24hrs
Ringer's solution	Maintenance solution	40-50 ml/kg	IV, SC, IP	q 24hrs
Ronidazole (Ronivet)	Tritrichomoniasis	30 mg/kg	PO	q 24hrs for 14 days
	(warning: low therapeutic margin)	20mg/kg	PO	q12hrs for 14 days
Roxithromycin	Susceptible infections	15 mg/kg	PO	q 24hrs
Rutin	Chylothorax, limb lymphedema	500 mg/kg^[5]	PO	q 24 hrs
Secnidazole	Giardia spp	30 mg/kg	PO	stat
Selegiline	Cognitive disorders	0.5 mg/kg	PO	q 24hrs
	Hyperadrenocorticism	1-2 mg/kg	PO	q 24hrs
Selamectin	Parasiticide	6 mg/kg	Topical	q 30days
Selenious acid, sodium selenite	Supplementation	0.3 mg/kg	PO	stat
Selenium	Pancreatitis	0.1 mg/kg	IV	stat
Senna	Constipation	5 ml/cat	PO	q 24hrs
Silver nitrate solution (0.5%)	Burns	Saturate wet dressing	Topically	q 12hrs
Sulfadiazine	Burns	Apply light coating	Topically	q 12hrs
Sodium bicarbonate	Renal failure	10-15 mg/kg	PO	q 8hrs
	Toxicoses	50 mg/kg	PO	q 8 - 12hrs
	Hyperkalemic crisis	2-3 mEq	IV	over 30 mins
	Urine alkalisation	0.65-5.85 g	PO	q 24hrs
Sodium chloride	Hypoadrenocorticism	1-5 g	PO	q 24hrs
	Hyponatremia, acute renal failure	1-4 g	PO	q 8hrs
	(0.9% soln)	40-50 ml/kg	IV, SQ, IP	q 24hrs
Sodium iodide, 20% soln	Sporothrix spp	0.5 ml/5kg	PO	q 24hrs
	Susceptible infections	20 mg/kg	PO	q 24hrs for 4 - 6 wks
Sodium phosphate	Hypercalcemia	Dilute 1-3 g with water (1:1) and give 10-20 ml	PO	q 8 - 24hrs until stools are soft
Sodium polystyrene sulphonate	Hypercalcemia	8-15 g/cat	PO	q 8hrs
Sodium thiopental	Anaesthesia	3-15 mg/kg	IV	to effect
Sorafenib	Chemotherapy	2 mg/kg	PO	once daily
Sorbitol (70% soln)	Stool softener	3 ml/kg	PO	stat
Sotalol (ß-adrenoceptor antagonist)	Ventricular arrhythmias	1-2 mg/kg	PO	q 12hrs
Spectinomycin	Susceptible infections	5-12 mg/kg	IM	q 12hrs
Spiramycin	Toxoplasmosis	12.5-23 mg/cat	PO	q 24hrs
Spironolactone	Diuretic: heart failure	2-4 mg/kg	PO
	Primary hyperaldosteronism	1 mg/kg	PO	q 12hrs
	Hepatic insufficiency	12.5 mg/cat	PO	q 24hrs
Spironolactone / hydrochlorothiazide	Diuretic, antihypertensive agent	1-2 mg/kg	PO	q 12-24hrs
Stanozolol	Anabolic agent, anaemia	1-2 mg/cat	PO	q 12hrs
		10-25 mg/kg	PO	q 7days
Staphage lysate	Immune stimulant	0.1-0.2 ml/cat	SQ	then
		incremental doses to 1.0ml	SQ	1 - 2 for a week, then
		0.5 ml	SQ	weekly for 10 - 12 weeks
Staphylococcal A	Immune stimulant	20 µg/2.75kg	IP	q 3 - 5 days
Streptomycin, dihydro	Leptospirosis, endocarditis, Mycobacterium spp, Yersinia pestis	10 mg/kg	IM	q6hrs
Styrid caricide (styrylpyridium chloride plus diethylcarbamazine)	Antiparasiticide	6.7mg/kg	PO	q 24hrs
Succinylcholine	Paralysis	0.06-0.11 mg/kg	IV	stat
Sucralfate	Gastrointestinal ulceration	250-500 mg/cat	PO	q 8 - 12hrs
	Hemorrhagic pancreatitis, vomiting with renal failure	40 mg/kg	PO	q 8hrs
Sufentanil (opioid agonist)	Premedicant with ACP	2 µg/kg (max dose 5 µg/kg)	IV	stat
Sulfadiazine	Nocardiosis	220 mg/kg	PO	for 1 treatment, then
		50-110 mg/kg	PO	q 12hrs
	Toxoplasmosis	15-50 mg/kg (with pyrimethamine)	PO	q 24hrs, divided, for 14 days
Sulfadiazine/Trimethoprim	Susceptible infections	30 mg/kg	PO, SQ	q 24hrs
	Meningitis	15 mg/kg	PO, IV	q 8 - 12hrs
	Nocardiosis	30-60 mg/kg	PO, SQ	q 12hrs
Sulfadimethoxine	Susceptible infections	25-50 mg/kg	PO, IM, IV	q 12 - 24hrs for max of 21days
	Coccidiosis	55 mg/kg (loading), then 27.5 mg/kg	PO	q 24hrs
Sulfaguanidine	Coccidiosis	100-200 mg/kg	PO	q 8hrs
Sulfamethazine, sulfamerazine	Coccidiosis	200 mg/kg (loading), then 50 mg/kg	PO	q12hrs
Sulfamethoxazole	Susceptible infections	100 mg/kg (loading), then 50 mg/kg	PO	q 12hrs
Sulfamethoxazole/Trimethoprim	Susceptible infections	15 mg/kg	PO	q 12hrs
Sulfasalazine	Lymphocytic plasmacytic enteritis	250 mg/cat	PO	q 8hrs for 3 days, then q 24hrs
	Irritable bowel disease	20-25 mg/kg	PO	q 12 -24hrs
	Susceptible bacterial infections	20 mg/kg	PO	q 12hrs
Sulfisoxazole	Urinary tract infections	50 mg/kg	PO	q 8hrs
Sulfobromophthalein sodium	Hepatic function testing	5 mg/kg	IV	collect serum 30 min after BSP injection
Suprofen ophthalmic	Allergic conjunctivitis	1%	Topically	q 8 - 12hrs
Tacrolimus	Otitis externa	0.1% lotion	topical	q 12hrs
Tamiflu	Viral disease	2-4 mg/kg	PO	q 12hrs within 48hrs of infection
Taurine	Taurine deficiency, dilated cardiomyopathy	250-500 mg/cat	PO	q 12hrs
	Central retinal degeneration	250 mg/cat	PO	q 12 - 24hrs
Telazol (Zoletil - Tiletamine / zolazepam)	Restraint	6.6 mg/kg	IM	stat
	Anaesthesia	11-15 mg/kg	IM	stat
Temaril-P (Trimeprazine and prednisolone)	Allergy	0.7-1.1 mg/kg	PO	q 12 - 24hrs
Terbinafine (Lamasil)	Fungal infections	20 - 30 mg/kg	PO	q 24hrs for 4 - 10 wks
Terbutaline sulphate (ß₂-adrenoceptor agonist)	Bronchodilator	0.01 mg/kg	SQ, IM	q 4hrs
		1.25-2.5 mg/cat	PO	q 8 hrs
Testosterone cypionate	Hormone replacement	2.2 mg/kg	IM	q 2 - 3 days
Testosterone, methyl	Anabolic effects	1-2 mg/kg; max 30 mg/day	PO	q 24hrs
Testosterone propionate	Feline symmetrical alopecia	12.5 mg with oestrogen	IM	stat
	Urinary incontinence	5-10 mg	IM	stat
		0.5-1.0 mg/kg	IM	q 2 - 3 days
Tetanus toxoid	Tetanus treatment	0.2 ml (test dose), then give 100-500 units/kg	SQ	watch for anaphylaxis for 30 min
Tetracycline	Acute bronchitis	10-25 mg/kg	PO	q 8 - 12krs
	Rickettsia spp	15 mg/kg	PO	q 8hrs for 21 days
	Mycobacterium spp	22 mg/kg	PO	q 8hrs
	Susceptible infections	1-5 mg/kg	IV, IM	q 8 - 12hrs
Theophylline	Bronchodilator	4 mg/kg	PO, IM	q 8 - 12hrs
Theo-Dur (Sustained release)	Bronchodilator	20-25 mg/kg	PO	q 24hrs, at night
Thiabendazole	Heartworm disease adulticide	35 mg/kg	PO	q 12hrs for 20 days
	Strongyloides	125 mg/kg	PO	q 24hrs for 3 days
Thiacetarsamide	Heartworm adulticide	2.2 mg/kg	IV	q 12hrs for 2 days
Thiamine (Vit B12)	Thiamine deficiency	1-2 mg/cat	IM	q 12hrs until regression of symptoms
		100-250 mg/kg	SQ	q 12hrs
Thiamylal sodium	Anaesthesia	8.8-13.3 mg/kg	IV	after tranquilisation
Thioguanine	Lymphocytic and granulocytic leukaemia	25 mg/m²	PO	q 24hrs for 1-5 days, then 130 days
Thyroid	Hypothyroidism	15-20 mg/kg/day	PO	q 24hrs
Thiopentone	General anaesthesia, status epilepticus	3-15 mg/kg	IV	to effect
Thyrotropin (TSH)	Provocative testing	1 IU/kg	IM	Collect baseline and post-TSH samples
	Acanthosis nigrans, hypothyroidism	1-2 IU	SQ	q 24hrs for 5 days
L-Thyroxine (levothyroxine)	Hypothyroidism	0.5 mg/m²	PO	q 12hrs
		20-30 µg/kg	PO	q 24hrs
Ticarcillin	Susceptible infections	33-50 mg/kg	IM, IV	q 6 - 8kg
		55-110 mg/kg	IM, Iv	q 4 - 6hrs
Ticarcillin/clavulanate	As above
Tiletamine / zolazepam	Minor procedure	9.7-11.9 mg/kg	IM	stat
	Castration	10.6-12.5 mg/kg	IM	do not exceed 72mg/kg with repeat doses
	Spey	14.3-15.8 mg/kg	IM	stat
Tinidazole	Gingivitis, Giardia spp	30 mg/kg	PO	q 24hrs for 14 days
Tiopronin	Cystine urinary calculi	15-20 mg/kg	PO	q 12hrs
Tolazoline	Xylazine reversal	2 mg/kg	IV	stat
Tolfenamic acid (Tolfedine)	Analgesia	4 mg/kg	IM, SQ, PO	q 24 hrs up to 5 days, 3 out of 7 days for long term Rx
Toltrazuril (Baycox)	Coccidiosis	5-20 mg/kg	PO	q 24hrs x 2-5 treatments
Toluene	Anthelmintic	267 mg/kg	PO	repeat in 2-4 weeks
Tramadol	Opioid analgesia	1-2 mg/kg	PO	q 8 - 12hrs
		12.5 mg/cat	PO	q12hrs
Tretinoin	Acne, nasal hyperkeratosis	0.25-0.5 mg/kg	PO	q 24hrs for 7 days
Triamcinolone	Gingivitis, pododermatitis	2-4 mg	PO	q 24 - 48hrs
	Hypokalemic polymyopathy	0.5-1.0 mg/kg	PO	q 24hrs
	Antiinflammatory	0.11-0.22 mg/kg	IM, SQ	stat
	Pannus, eosinophilic keratitis, episcleritis	4 mg	Subconjunctival	stat
	Esophageal stricture	1-2 mg/cat	submucosal	stat
	Glucocorticoid effect	0.1-0.2 mg/kg	IM, SQ	q 24hrs
Triamterene	Diuretic	1-2 mg/kg	PO	q 12hrs
Trientine hydrochloride	Chelating agent	10-15 mg/kg	PO	q 12hrs
Triethylene thiophosphoramide	Bladder neoplasia	30 mg/m²	Intravesicular	q 3 - 4wks
Thiethylperazine	Antipsychotic	0.13-0.2 mg/kg	IM	q 8 - 12hrs
Trifluoperazine	Antipsychotic	0.03 mg/kg	IM	q 12hrs
Triflupromazine	Behaviour modification	0.1-0.3 mg/kg	IM, PO	q 8 - 12hrs
Trifluridine ophthalmic	herpes infection	0.1% soln, 1-2 drops	Topically	q 34 - 8hrs
Triiodothyronine (T3)	Hypothyroidism	4.4 µg/kg	PO	q 8 - 12hrs
Trilostane	Cushing's syndrome	30 mg/kg	PO	q 12 - 24 hrs
Trimethoprim/sulfadiazine	Susceptible infections	15 mg/kg	PO, SQ, IV	q 8 - 12hrs
Tripelennamine	Antihistamine	1 mg/kg	PO, IM	q 12hrs
Trypan blue	Feline babesiosis	4 mg/kg	IV	stat
Tylosin	GI bacterial overgrowth	6.6-11 mg/kg	IM	q 12 - 24hrs
	Chronic colitis	25 mg	PO	q 8hrs
Urea	Osmotic	300 mg	IV	stat
Urokinase	Aortic thromboembolism	90,000 IU over 20 minutes, then 45,000 IU CRI	IV	for up to 24 hrs
Urofollitropin	Hypogonadotropic anovulation	2 mg/cat	IM	q 24hrs
Ursodeoxycholic acid	Chronic hepatitis	5-15 mg/kg	PO	q 24hrs
Valproic acid	Epilepsy	25-65 mg/kg	PO	with Phenobarbital
		10-105 mg/kg	PO	alone
Vanadium	Hyperglycaemia	0.2 mg/kg	PO	q 24hrs
Vasopressin, aqueous	Central diabetes insipidus	10 mU/cat	IV, IM	as needed
Vasopressin, tannate in oil	Central diabetes insipidus	2.5-5.0 U/cat	IM	q 1- 7 days
Vecuronium bromide	Paralytic agent for controlled anaesthesia	40 µg/kg	IV	over 30 min
Verapamil (calcium channel blocker)	Supraventricular arrhythmias	10-15 mg/kg	PO	q 24hrs, divided
	Conversion of rapid supraventricular tachycardia	1.1-4.4 mg/kg	PO	q 8 - 12hrs
Vidarabine	Ocular herpesviral infection	1/8 inch	Topically	q 6 - 8hrs
Vinblastine	Mast cell tumour, lymphosarcoma	0.1-0.4 mg/kg	IV	q7-14 days
Vincristine	Thrombocytopenia	0.01-0.025 mg/kg	IV	q 7-10 days
	Lymphosarcoma	0.5-1.0 mg/m²	IV	once weekly
	Neoplasia	0.5-0.75 mg/m²	IV	q 7 - 14days
Viokase	Exocrine pancreatic insufficiency	325 mg	PO	with each meal
Vitamin A	Dietary supplement	400 U/kg	PO	q 24hrs for 10d
Vitamin B1	see Thiamine
Vitamin B2		5-10 mg/cat	PO	q 24hrs
Vitamin B complex	Vitamin B deficiency	0.5-1.0 ml	IV, IM, SQ	q 24hrs
Vitamin C	see Ascorbic acid
Vitamin D (dihydrotachysterol)	Hypocalcemia	0.02 mg/kg	PO	Initially, then
		0.01 mg/kg	PO	q 24 - 48hrs
Vitamin D2 (ergocalciferol)	Hypocalcemia	4000-6000 U/kg	PO	q 24hrs, initially, then
		500-1000 U/kg	PO	q 24 - 48hrs
Vitamin D3 (calcitriol - 1-25, dihydroxy vitamin D3)	Hypocalcemia	0.03-0.06 µg/kg	PO	q 24hrs
	Chronic renal disease	0.025 µg/kg	PO	q 24hrs
Vitamin E	Vitamin E deficient myositis, [yellow%20fat%20disease.htm steatitis]	10-20 IU/kg	PO	q 12hrs
	autoimmune skin diseases	400-600 IU/cat	PO	q 12hrs
Vitamin K1	Deficiency, hepatopathy	1-3mg/kg	SQ, PO	q 12hrs for 4 - 6 weeks
		5mg/kg	PO	q 24hrs, divided doses
Voriconazole	Aspergillosis	5 mg/kg	PO	q 24hrs. May cause neurotoxicity
Warfarin	Aortic thromboembolism	0.06-0.20 mg/kg	PO	q 24hrs. Maintain PTT at 2 - 2.5 times normal
Xylazine	Muscle relaxation	1.1-2.2mg/kg	IM, SQ	stat
	Emetic	0.44mg/kg	IM
Zafirlukast	Leukotriene receptor antagonist	0.15-0.2mg/kg	PO	q 12 - 24hrs
Zidovudine (AZT)	Antiviral	5-20 mg/kg	SQ, PO	q 8 - 12 hrs
Zinc	Antioxidant	2-3 mg/kg	PO	q 24 hrs
Zithromax (Azithromycin)]	Susceptible infections	5 mg/kg	PO	q 24 - 48 hrs
	Susceptible infections	80 mg stat	PO	weekly x 3

Zonisamide	Epilepsy	5 mg/kg	PO	q 12 hours

References

↑ Clark CH (1976) Penicillins in veterinary practice. Mod Vet Pract 57(12):1019-1023
↑ Dauphin F & Hamel E (1990) Muscarinic receptor subtype mediating vasodilation feline middle cerebral artery exhibits M3 pharmacology. Eur J Pharmacol 178(2):203-213
↑ ^3.0 ^3.1 Moretti A et al (1979) A review of pharmacological studies on nicergoline. Arzneimittelforschung 29(8a):1223-1227
↑ Slingerland LI et al (2008) Growth hormone excess and the effect of octreotide in cats with diabetes mellitus. Domest Anim Endocrinol 35(4):352-361
↑ Kopko SH (2005) The use of rutin in a cat with idiopathic chylothorax. Can Vet J 46(8):729-731